NAD+ (NICOTINAMIDE ADENINE DINUCLEOTIDE)
Compound Overview
Nicotinamide Adenine Dinucleotide (NAD+) is a naturally occurring dinucleotide coenzyme present in all living cells. Composed of two nucleotides joined through their phosphate groups—one containing adenine and the other nicotinamide—NAD+ serves as a fundamental cofactor in numerous oxidation-reduction (redox) reactions and is essential for cellular energy metabolism and biochemical homeostasis.
Researchers have extensively investigated NAD+ for its central role in mitochondrial function, oxidative phosphorylation, glycolysis, the tricarboxylic acid (TCA) cycle, and cellular respiration. Beyond its function as an electron carrier, NAD+ also serves as a substrate for several classes of enzymes, including sirtuins (SIRT1–7), poly(ADP-ribose) polymerases (PARPs), and CD38 ectoenzymes, making it an important research molecule in studies involving cellular signaling, DNA repair, metabolic regulation, and mitochondrial biology.
As an investigational research compound, NAD+ supports laboratory studies involving molecular biology, biochemistry, cellular metabolism, mitochondrial physiology, and enzymology under controlled experimental conditions.
Research Applications
Research applications are presented for educational and informational purposes only and do not imply approved therapeutic uses.
Product Specifications
| Purity | 99% |
| Appearance | White to Off-White Lyophilized Powder |
| Chemical Name | β-Nicotinamide Adenine Dinucleotide (Oxidized Form) |
| Molecular Formula | C21H27N7O14P2 |
| Molecular Weight | 663.43 g/mol |
| CAS Number | 53-84-9 |
| Storage | Store refrigerated at 2–8°C (36–46°F). For extended laboratory storage, maintain at −20°C or below. Protect from moisture and light. |
| Research Grade | Laboratory Research Use Only |
Available Sizes
Pricing: Inquire — contact our team for current pricing and availability.
Product Documentation
Every batch of NAD+ (NICOTINAMIDE ADENINE DINUCLEOTIDE) is independently tested and assigned its own lot number. When you request documentation, include the product name and lot number printed on your vial so we can send the COA, HPLC, and MS data specific to the batch in your hand — not a generic reference sample. Request documentation →
Laboratory Handling
Store refrigerated immediately upon receipt to preserve compound stability. For extended laboratory storage, freezing at −20°C or below is recommended. Protect the lyophilized material from moisture, excessive heat, and direct light. Following reconstitution, avoid repeated freeze-thaw cycles, as these may reduce chemical stability. Allow the vial to equilibrate to room temperature before opening to minimize condensation, and always use sterile laboratory equipment together with appropriate aseptic laboratory techniques. This product is intended for use only by qualified research personnel operating in controlled laboratory environments.
Selected Scientific Literature
- Verdin E. NAD+ in Aging, Metabolism, and Neurodegeneration. Science.
- Ying W. NAD+ and NADH in Cellular Functions and Cell Death. Frontiers in Bioscience.
- Cantó C, Menzies KJ, Auwerx J. NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act Between Mitochondria and the Nucleus. Cell Metabolism.
- Covarrubias AJ, Perrone R, Grozio A, Verdin E. NAD+ Metabolism and Its Roles in Cellular Processes During Ageing. Nature Reviews Molecular Cell Biology.
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| Compound | Purity | Molecular Weight | CAS Number |
|---|---|---|---|
| NAD+ (NICOTINAMIDE ADENINE DINUCLEOTIDE) | 99% | 663.43 g/mol | 53-84-9 |
| EPITALON (EPITHALON) | 99% | 390.35 g/mol | 307297-39-8 |
| SS-31 (ELAMIPRETIDE) | 99% | 639.79 g/mol | 736992-21-5 |
| MOTS-c | 99% | 2,174.6 g/mol | 1627580-64-6 |
| HMG (HUMAN MENOPAUSAL GONADOTROPIN) | 99% | — | Not Applicable (Biological Gonadotropin Preparation) |
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