HMG (HUMAN MENOPAUSAL GONADOTROPIN)
Compound Overview
Human Menopausal Gonadotropin (HMG) is a purified gonadotropin preparation containing both follicle-stimulating hormone (FSH) and luteinizing hormone (LH) biological activity. Traditionally isolated from the urine of postmenopausal women, HMG consists primarily of glycoprotein hormones that regulate reproductive endocrine function through selective activation of the FSH receptor (FSHR) and luteinizing hormone/choriogonadotropin receptor (LHCGR).
Researchers have extensively investigated HMG as a valuable tool for studying reproductive endocrinology, gonadal physiology, follicular development, steroidogenesis, gametogenesis, and pituitary-gonadal axis regulation. Its dual gonadotropin activity enables experimental investigation of coordinated endocrine signaling pathways involved in ovarian and testicular physiology, receptor pharmacology, intracellular signaling, and hormone-mediated cellular responses.
As an investigational research product, HMG supports laboratory studies involving reproductive biology, molecular endocrinology, hormone receptor signaling, peptide glycoprotein biology, and structure-function relationships in controlled experimental settings.
Research Applications
Research applications are presented for educational and informational purposes only and do not imply approved therapeutic uses.
Product Specifications
| Purity | 99% |
| Appearance | White to Off-White Lyophilized Powder |
| Composition | Human Menopausal Gonadotropin (FSH and LH Activity) |
| Potency | Common laboratory preparations expressed in International Units (IU) |
| CAS Number | Not Applicable (Biological Gonadotropin Preparation) |
| Storage | Store refrigerated at 2–8°C (36–46°F). For extended laboratory storage, maintain at −20°C or below. Protect from moisture and light. |
| Research Grade | Laboratory Research Use Only |
Available Sizes
Pricing: Inquire — contact our team for current pricing and availability.
Product Documentation
Every batch of HMG (HUMAN MENOPAUSAL GONADOTROPIN) is independently tested and assigned its own lot number. When you request documentation, include the product name and lot number printed on your vial so we can send the COA, HPLC, and MS data specific to the batch in your hand — not a generic reference sample. Request documentation →
Laboratory Handling
Store refrigerated immediately upon receipt to preserve biological activity. For extended laboratory storage, freezing at −20°C or below is recommended. Protect the lyophilized preparation from moisture, excessive heat, and direct light. Following reconstitution, avoid repeated freeze-thaw cycles, as these may reduce glycoprotein stability and biological activity. Allow the vial to equilibrate to room temperature before opening to minimize condensation, and always use sterile laboratory equipment together with appropriate aseptic laboratory techniques. This product is intended for use only by qualified research personnel operating in controlled laboratory environments.
Selected Scientific Literature
- Pierce JG, Parsons TF. Glycoprotein Hormones: Structure and Function. Annual Review of Biochemistry.
- Simoni M, Gromoll J, Nieschlag E. The Follicle-Stimulating Hormone Receptor: Biochemistry, Molecular Biology, Physiology, and Pathophysiology. Endocrine Reviews.
- Ascoli M, Fanelli F, Segaloff DL. The Lutropin/Choriogonadotropin Receptor: A 2002 Perspective. Endocrine Reviews.
- Richards JS, Pangas SA. The Ovary: Basic Biology and Clinical Implications. Journal of Clinical Investigation.
Compare with related compounds
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| Compound | Purity | Molecular Weight | CAS Number |
|---|---|---|---|
| HMG (HUMAN MENOPAUSAL GONADOTROPIN) | 99% | — | Not Applicable (Biological Gonadotropin Preparation) |
| EPITALON (EPITHALON) | 99% | 390.35 g/mol | 307297-39-8 |
| SS-31 (ELAMIPRETIDE) | 99% | 639.79 g/mol | 736992-21-5 |
| MOTS-c | 99% | 2,174.6 g/mol | 1627580-64-6 |
| NAD+ (NICOTINAMIDE ADENINE DINUCLEOTIDE) | 99% | 663.43 g/mol | 53-84-9 |
Need a Certificate of Analysis?
Request COAs, HPLC, or MS documentation for HMG (HUMAN MENOPAUSAL GONADOTROPIN).