SLU-PP-332
Compound Overview
SLU-PP-332 is a synthetic small-molecule investigational compound developed as a pan-agonist of the estrogen-related receptor (ERR) family, exhibiting activity at ERRα, ERRβ, and ERRγ, with the greatest potency toward ERRα. Although frequently marketed alongside research peptides, SLU-PP-332 is not a peptide; it is a low-molecular-weight organic compound belonging to the acylhydrazone (benzohydrazide) chemical class.
Researchers have investigated SLU-PP-332 as a chemical probe for studying mitochondrial biology, oxidative metabolism, nuclear receptor signaling, and cellular energy regulation. Experimental studies have demonstrated activation of transcriptional programs involved in mitochondrial function and oxidative phosphorylation through estrogen-related receptor (ERR) signaling pathways. Because ERRs regulate genes associated with mitochondrial biogenesis and aerobic metabolism, SLU-PP-332 has become an important research tool in molecular metabolism, exercise physiology, and nuclear receptor biology. Current evidence is limited to cellular and animal studies, and there are no approved human therapeutic indications.
Research Applications
Research applications are presented for educational and informational purposes only and do not imply approved therapeutic uses.
Product Specifications
| Purity | 99% |
| Appearance | White to Off-White Powder |
| Chemical Name | (E)-4-Hydroxy-N'-(naphthalen-2-ylmethylene)benzohydrazide |
| Molecular Formula | C18H14N2O2 |
| Molecular Weight | 290.32 g/mol |
| CAS Number | 303760-60-3 |
| Storage | Store refrigerated at 2–8°C (36–46°F). For long-term laboratory storage, maintain in a tightly sealed container at −20°C and protect from moisture and light. |
| Research Grade | Laboratory Research Use Only. Note: SLU-PP-332 is a synthetic small molecule rather than a peptide. |
Available Sizes
Pricing: Inquire — contact our team for current pricing and availability.
Product Documentation
Every batch of SLU-PP-332 is independently tested and assigned its own lot number. When you request documentation, include the product name and lot number printed on your vial so we can send the COA, HPLC, and MS data specific to the batch in your hand — not a generic reference sample. Request documentation →
Laboratory Handling
Store refrigerated immediately upon receipt to preserve compound stability. For extended laboratory storage, maintain at −20°C or below in a dry, light-protected environment. Protect the material from excessive heat, moisture, and prolonged air exposure. Following dissolution, prepare solutions using appropriate laboratory-grade solvents and avoid repeated freeze-thaw cycles where possible. Handle using sterile laboratory equipment and established laboratory safety procedures. This product is intended exclusively for qualified research personnel conducting controlled laboratory investigations.
Selected Scientific Literature
- Billon C, et al. Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity. ACS Chemical Biology.
- Billon C, et al. A Synthetic ERR Agonist Alleviates Metabolic Syndrome. Journal of Pharmacology and Experimental Therapeutics.
- Avdagic A, Billon C, Burris TP. Estrogen-Related Receptor Modulators: Structural Determinants for Selectivity and Efficacy. Journal of Medicinal Chemistry.
- Gatto GJ, Ao Z, Kearse MG, et al. CREP-1: A Small-Molecule Tool Compound That Selectively Activates Estrogen-Related Receptor Alpha (ERRα). Cell Chemical Biology.
Compare with related compounds
Other compounds researchers commonly browse alongside SLU-PP-332 in Longevity & Mitochondrial.
| Compound | Purity | Molecular Weight | CAS Number |
|---|---|---|---|
| SLU-PP-332 | 99% | 290.32 g/mol | 303760-60-3 |
| EPITALON (EPITHALON) | 99% | 390.35 g/mol | 307297-39-8 |
| SS-31 (ELAMIPRETIDE) | 99% | 639.79 g/mol | 736992-21-5 |
| MOTS-c | 99% | 2,174.6 g/mol | 1627580-64-6 |
| NAD+ (NICOTINAMIDE ADENINE DINUCLEOTIDE) | 99% | 663.43 g/mol | 53-84-9 |
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