GHK-Cu (COPPER TRIPEPTIDE-1)
Compound Overview
GHK-Cu, also known as Copper Tripeptide-1, is a naturally occurring copper-binding tripeptide composed of the amino acid sequence glycyl-L-histidyl-L-lysine (GHK) complexed with a divalent copper ion (Cu2+). First identified in human plasma, GHK-Cu is also naturally present in saliva and urine and has been extensively investigated for its role in cellular signaling, extracellular matrix biology, and tissue physiology.
The peptide exhibits a high affinity for copper ions, forming a stable complex that has become an important research tool for studying copper transport, metallopeptide chemistry, cellular communication, and peptide-mediated biological processes. Researchers continue to investigate GHK-Cu in experimental models examining gene expression, extracellular matrix remodeling, collagen biology, angiogenesis, oxidative stress responses, and molecular signaling pathways.
As an investigational peptide, GHK-Cu supports laboratory research involving peptide chemistry, molecular biology, regenerative biology, metalloprotein interactions, and structure-activity relationships under controlled experimental conditions.
Research Applications
Research applications are presented for educational and informational purposes only and do not imply approved therapeutic uses.
Product Specifications
| Purity | 99% |
| Appearance | Blue Lyophilized Powder |
| Sequence | Gly-His-Lys·Cu2+ |
| Molecular Formula | C14H24CuN6O4 |
| Molecular Weight | 403.93 g/mol |
| CAS Number | 89030-95-5 |
| Storage | Store refrigerated at 2–8°C (36–46°F). For extended laboratory storage, maintain at −20°C or below. Protect from moisture and light. |
| Research Grade | Laboratory Research Use Only |
Available Sizes
Pricing: Inquire — contact our team for current pricing and availability.
Product Documentation
Every batch of GHK-Cu (COPPER TRIPEPTIDE-1) is independently tested and assigned its own lot number. When you request documentation, include the product name and lot number printed on your vial so we can send the COA, HPLC, and MS data specific to the batch in your hand — not a generic reference sample. Request documentation →
Laboratory Handling
Store refrigerated immediately upon receipt to preserve peptide stability. For extended laboratory storage, freezing at −20°C or below is recommended. Protect the lyophilized peptide from moisture, excessive heat, and direct light. Avoid repeated freeze-thaw cycles following reconstitution, as these may reduce peptide stability and copper complex integrity. Allow the vial to equilibrate to room temperature before opening to minimize condensation, and always use sterile laboratory equipment together with appropriate aseptic laboratory techniques. This product is intended for use only by qualified research personnel operating in controlled laboratory environments.
Selected Scientific Literature
- Pickart L, Margolina A. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. International Journal of Molecular Sciences.
- Pickart L. The Human Tripeptide GHK and Tissue Remodeling. Journal of Biomaterials Science, Polymer Edition.
- Maquart FX, Bellon G, Chaqour B, et al. In Vivo Stimulation of Connective Tissue Accumulation by the Tripeptide-Copper Complex Glycyl-L-Histidyl-L-Lysine-Cu2+. Journal of Clinical Investigation.
- Pickart L, Vasquez-Soltero JM, Margolina A. GHK Peptide as a Natural Modulator of Multiple Cellular Pathways. BioMed Research International.
Compare with related compounds
Other compounds researchers commonly browse alongside GHK-Cu (COPPER TRIPEPTIDE-1) in Healing & Recovery.
| Compound | Purity | Molecular Weight | CAS Number |
|---|---|---|---|
| GHK-Cu (COPPER TRIPEPTIDE-1) | 99% | 403.93 g/mol | 89030-95-5 |
| BPC-157 | 99% | 1,419.53 g/mol | 137525-51-0 |
| TB-500 (THYMOSIN BETA-4 FRAGMENT) | 99% | 4,963.44 g/mol | 77591-33-4 (Thymosin Beta-4; TB-500 itself does not have a universally recognized CAS assignment, and suppliers often reference the parent peptide.) |
| BPC-157 + TB-500 BLEND | 99% (Each Peptide) | — | Blend – Not Applicable |
| Glow Blend (Cu50 + TB10 + BPC10) | 99% (Each Peptide Component) | 70 mg | — |
Need a Certificate of Analysis?
Request COAs, HPLC, or MS documentation for GHK-Cu (COPPER TRIPEPTIDE-1).