CJC-1295 (DAC)
Compound Overview
CJC-1295 (With DAC) is a synthetic analog of growth hormone-releasing hormone (GHRH) engineered with a Drug Affinity Complex (DAC®) that enables reversible binding to circulating serum albumin. This structural modification significantly prolongs the peptide's half-life compared with native GHRH and non-DAC analogs, making it an important investigational compound for studying sustained endocrine signaling and long-acting peptide pharmacology.
By selectively activating the growth hormone-releasing hormone receptor (GHRH-R), CJC-1295 (With DAC) has become a valuable research tool for investigating growth hormone physiology, intracellular signaling pathways, receptor pharmacology, peptide engineering, and pharmacokinetics. The extended duration of receptor stimulation afforded by the DAC modification allows researchers to examine prolonged biological responses in experimental models.
As an investigational peptide, CJC-1295 (With DAC) supports laboratory research involving endocrine biology, peptide stability, long-acting drug delivery technologies, molecular signaling, and structure-activity relationships.
Research Applications
Research applications are presented for educational and informational purposes only and do not imply approved therapeutic uses.
Product Specifications
| Purity | 99% |
| Appearance | White to Off-White Lyophilized Powder |
| Molecular Formula | C165H269N47O46 |
| Molecular Weight | 3,364.90 g/mol |
| Storage | Store refrigerated at 2–8°C (36–46°F). For extended laboratory storage, maintain at −20°C or below. Protect from moisture and light. |
| CAS Number | 863288-34-0 |
| Research Grade | Laboratory Research Use Only |
Available Sizes
Pricing: Inquire — contact our team for current pricing and availability.
Product Documentation
Every batch of CJC-1295 (DAC) is independently tested and assigned its own lot number. When you request documentation, include the product name and lot number printed on your vial so we can send the COA, HPLC, and MS data specific to the batch in your hand — not a generic reference sample. Request documentation →
Laboratory Handling
Store refrigerated immediately upon receipt to preserve peptide stability. For extended laboratory storage, freezing at −20°C or below is recommended. Protect the lyophilized peptide from moisture, excessive heat, and direct light. Avoid repeated freeze-thaw cycles following reconstitution, as these may reduce peptide integrity. Allow the vial to equilibrate to room temperature before opening to minimize condensation, and always use sterile laboratory equipment together with appropriate aseptic laboratory techniques. This product is intended for use only by qualified research personnel operating in controlled laboratory environments.
Selected Scientific Literature
- Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA. Prolonged Stimulation of Growth Hormone (GH) and Insulin-Like Growth Factor-I Following a Single Injection of CJC-1295 in Healthy Adults. The Journal of Clinical Endocrinology & Metabolism.
- Jette L, Léger R, Thibaudeau K, et al. Human Growth Hormone-Releasing Factor Coupled to Drug Affinity Complex (DAC®) Technology Generates a Long-Acting GHRH Analog. Journal of Controlled Release.
- Bowers CY. Growth Hormone-Releasing Hormone Analogs and Growth Hormone Secretagogues. Endocrine.
- Thorner MO. Growth Hormone-Releasing Hormone and Growth Hormone Secretagogues: Basic Biology and Clinical Research. Endocrine Reviews.
Compare with related compounds
Other compounds researchers commonly browse alongside CJC-1295 (DAC) in Growth Hormone & Secretagogues.
| Compound | Purity | Molecular Weight | CAS Number |
|---|---|---|---|
| CJC-1295 (DAC) | 99% | 3,364.90 g/mol | 863288-34-0 |
| IPAMORELIN | 99% | 711.85 g/mol | 170851-70-4 |
| CJC-1295 & IPAMORELIN BLEND | 99% (Each Peptide) | — | Blend – Not Applicable |
| CJC-1295 (No DAC) | 99% | 3,364.0 g/mol | 86168-78-7 (Modified GRF (1-29)) |
| IGF-1 LR3 (LONG R3 INSULIN-LIKE GROWTH FACTOR-1) | 99% | 9,203.3 g/mol | 946870-92-4 |
Need a Certificate of Analysis?
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